Allergenic Component of a Liverwort: A Sesquiterpene Lactone

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Science  10 Oct 1969:
Vol. 166, Issue 3902, pp. 239-240
DOI: 10.1126/science.166.3902.239


Frullania spp. (Hepaticae, Jungermanniales) are agents of allergies. Extraction and fractionation of Frullania tamarisci has given, as the only allergenic component isolated, a levorotatory crystalline sutbstance, the structure of which is demonstrated. It is a sesquiterpene lactone. The racemic (±) form is isolated from a mixed sample of Frullania tamarisci and Frullania dilatata; the dextrorotatory form, from Frullania dilatata. The observed allergenic properties are shared by some other-sesquiterpene lactones.

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