Keratohyalin: Extraction and in vitro Aggregation

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Science  10 Oct 1969:
Vol. 166, Issue 3902, pp. 250-251
DOI: 10.1126/science.166.3902.250


Kercatohyalin can be extracted from epidermis by 1.0 molar phosphate buffer (pH 7.0), as demonstrated histochemically and ultrastructurally. If the extracted material is dialyzed against water, it aggregates to form granules that are similar to keratolhyalin granules in size, shape, histochemical staining, and electron opacity.

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