Elution of Glomerular Bound Antibodies in Experimental Streptococcal Glomerulonephritis

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Science  21 Nov 1969:
Vol. 166, Issue 3908, pp. 1032-1033
DOI: 10.1126/science.166.3908.1032


lmmnunoglobulin G, eluted from glomeruli of rats with streptococcal glomerulonephritis, reacts with type 12 M protein of the streptococcus but not with other streptococcal or renal antigens. Thtrefore, this disease may be madiated by fixation of antigen-antibody complexes consisting of streptococcal M protein and type-specific antibody.

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