Cystine: Compartmentalization within Lysosomes in Cystinotic Leukocytes

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Science  28 Nov 1969:
Vol. 166, Issue 3909, pp. 1152-1154
DOI: 10.1126/science.166.3909.1152


The large amount of cystine compartmentalized in cystinotic leukocytes cosediments in isopycnic sucrose density gradients with dense lysosomal particles, within which it is presumably contained. Such cystine appears to be primarily noncrystalline in these organelles.

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