Altered Ribosomal Protein in Streptomycin-Dependent Escherichia coli

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Science  05 Dec 1969:
Vol. 166, Issue 3910, pp. 1282-1284
DOI: 10.1126/science.166.3910.1282


We have compared the 30S ribosomal proteins of strains of Escherichia coli sensitive to and dependent on streptomycin and identified a single protein that is functionally altered in the ribosomes dependent on streptomycin. This protein (30S-15) is the same protein that is functionally altered in ribosomes resistant to streptomycin.

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