Kasugamycin Resistance: 30S Ribosomal Mutation with an Unusual Location on the Escherichia coli Chromosome

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Science  02 Jan 1970:
Vol. 167, Issue 3914, pp. 56-58
DOI: 10.1126/science.167.3914.56


A mutation in Escherichia coli to resistance to the aminoglycoside antibiotic kasugamycin alters the 30S ribosomal subunit. Though all other known 30S ribosomal mutations are located in a cluster in the streptomycin region, kasugamycin resistance is located at a distance from this region, near the leucine region.

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