Placental Transfer of a Substituted Pteridine from Fetus to Mother

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Science  13 Feb 1970:
Vol. 167, Issue 3920, pp. 988-990
DOI: 10.1126/science.167.3920.988


In sito near-term sheep placentas transferred triamterene (2,4,7-triamino-6-phenyl-pteridine) from the fetus much more rapidly than to the fetus. This differential transfer effect may significantly influence the distribution of exogenous and endogenous compounds between the maternal and fetal compartments.