Late DNA Replication in Male Mouse Meiotic Chromosomes

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Science  20 Feb 1970:
Vol. 167, Issue 3921, pp. 1133-1134
DOI: 10.1126/science.167.3921.1133


Parts of the male mouse meiotic complement comprising the Y chromosome, the whole X chromosome, and near-centromeric parts of autosomal bivalents are synthesized late, as judged by tritiated thymidine autoradiography. This confirms the occurrence of end-to-end association between X and Y chromosomes and suggests that paired heterochromatic segments in autosomes must synthesize DNA at the same time.

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