[8-Arginine]-Vasopressinoic Acid: An Inhibitor of Rabbit Kidney Adenyl Cyclase

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Science  20 Feb 1970:
Vol. 167, Issue 3921, pp. 1134-1135
DOI: 10.1126/science.167.3921.1134


Neurohypophyseal hormnones and several synthetic analogs stimulate adenyl cyclase prepared from rabbit kidney medullary tissue. [8-Arginine]-vasopressinoic acid inhibits the stimulation of medullary adenyl cyclase by neurohypophyseal peptides but does not influence the action of parathyroid hormone on adenyl cyclase from kidiney cortex.