Fetal Response to Viral Infection: Interferon Production in Sheep

See allHide authors and affiliations

Science  20 Feb 1970:
Vol. 167, Issue 3921, pp. 1139-1141
DOI: 10.1126/science.167.3921.1139


When virus was inoculated intravenously during the third trimester, the gestating ewe produced only low amounts of serum interferon, whereas the fetal lamb had the capacity to produce extremely high amounts. There was no evidence of transplacental transfer of interferon between mother and fetus in either direction.

Stay Connected to Science