Encapsidation of Free Host DNA by Simian Virus 40: A Simian Virus 40 Pseudovirus

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Science  10 Apr 1970:
Vol. 168, Issue 3928, pp. 268-270
DOI: 10.1126/science.168.3928.268


Under specified growth conditions, simian virus 40 encapsidated host DNA in a noncircular form free of viral DNA. Two bands of virus particles were present in cesium chloride equilibrium density centrifugation. The host DNA species contained in the upper band was of a lower molecular weight than the DNA present in the mature virus in the lower band.

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