Acetylcholine Sensitivity of Muscle Fiber Membranes: Mechanism of Regulation by Motoneurons

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Science  17 Apr 1970:
Vol. 168, Issue 3929, pp. 372-373
DOI: 10.1126/science.168.3929.372


Inhibitors of RNA and protein synthesis prevent the development of acetylcholine supersensitivity in organ-cultured rat diaphragm muscle but do not affect established acetylcholine sensitivity. The restriction of this sensitivity in innervated muscle apparently involves muscle fibers.

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