DNA Synthesis during Yeast Sporulation: Genetic Control of an Early Developmental Event

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Science  24 Apr 1970:
Vol. 168, Issue 3930, pp. 493-494
DOI: 10.1126/science.168.3930.493


In yeast the mating type alleles a and a also control sporulation; heterozygous strains (a/a) sporulate while homozygous strains (a/a or a/a) do not. Net DNA synthesis, an early event preceding sporulation, occurred normally in the heterozygous strains but did not occur in the homozygous strains. Therefore, the a/a allelles also influence early development well before spore formation begins.

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