Myxovirus Antibody Increases in Human Connective Tissue Disease

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Science  22 May 1970:
Vol. 168, Issue 3934, pp. 982-984
DOI: 10.1126/science.168.3934.982


Antibodies to measles and parainfluenza type 1 viruses were significantly increased in systemic lupus erythematosus and Reiter's syndrome. Of the individuals with highest titers of measles antibody, 75 percent had neurologic illness. Persistent virus infection may be a factor in the pathogenesis of these diseases.

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