Vasopressin: Effect on Deformability of Urinary Surface of Collecting Duct Cells

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Science  29 May 1970:
Vol. 168, Issue 3935, pp. 1093-1095
DOI: 10.1126/science.168.3935.1093


In isolated renal collecting ducts vasopressin decreased the negative pressure required to suck a hemispherical bulge of the epitheliat cells' urinary surface into the tip of a micropipette. Increased surface deformability may be related to the increased permeability to water which also occurs in the apex of the cells in response to the hormone.

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