Australia Antigen: Distribution during Cohn Ethanol Fractionation of Human Plasma

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Science  19 Jun 1970:
Vol. 168, Issue 3938, pp. 1462-1464
DOI: 10.1126/science.168.3938.1462


When plasma containing a hepatitis-associated antigen (Au/SH) is fractionated, the antigen is localized in fractions III and IV with none in fraction II and only small amounts in fractions I and V. The amount of antigen found in each of these fractions is probably not predictive of clinical infectivity of Cohn ethanol fractions from normnal pooled plasna.