Droplet Countercurrent Chromatography

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Science  03 Jul 1970:
Vol. 169, Issue 3940, pp. 54-56
DOI: 10.1126/science.169.3940.54


A new form of countercurrent chromatography, named droplet counter-current chromatography, has been developed. This all-liquid separation technique is based on the partitioning of solute between a steady stream of droplets of moving phase and a column of surrounding stationary liquid phase. Milligram quantities of dinitrophenyl (DNP) amino acids were separated with an efficiency comparable to that of gas chromatography.

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