Antigen Receptor Molecules: Inhibition by Antiserum against Kappa Light Chains

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Science  31 Jul 1970:
Vol. 169, Issue 3944, pp. 487-488
DOI: 10.1126/science.169.3944.487


Rabbit antiserum against mouse kappa chains, the predominant class of light chains found in mouse immunoglobulins, inhibits the immune response in vitro of mouse spleen cells to erythrocyte antigens. The inhibition becomes irreversible if the mouse spleen cells are treated briefly with both antiserum to kappa chains and complement.

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