Replicating DNA: Structure of Colicin Factor E1

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Science  07 Aug 1970:
Vol. 169, Issue 3945, pp. 590-592
DOI: 10.1126/science.169.3945.590


Replicating circular molecules of colicin factor E1 have been isolated from minicells produced by a colicinogenic derivative of Escherichia coli P678-54. The replicating structures observed in electron micrographs are circular molecules with two branched points. Several structures found among the replicating molecules are interpretable as replicating rolling circles.