Tilorone Hydrochloride: An Orally Active Antiviral Agent

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Science  18 Sep 1970:
Vol. 169, Issue 3951, pp. 1213-1214
DOI: 10.1126/science.169.3951.1213


Tilorone hydrochloride, 2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one dihydrochloride, given orally to mice before they are infected is active against at least nine viruses of both RNA and DNA groups. The compound is effective when given prophylactically; the optimum time of treatment depends on the route of infection.

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