Synaptic Potentials Recorded in Cell Cultures of Nerve and Muscle

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Science  25 Sep 1970:
Vol. 169, Issue 3952, pp. 1331-1333
DOI: 10.1126/science.169.3952.1331


Initially dissociated spinal cord and muscle cells derived from chick embryos differentiate sufficiently in tissue culture to form functional synaptic contacts. Spontaneous and evoked potentials recorded with intracellular microelectrodes resemble synaptic responses of adult spinal cord and neuromuscular junctions.

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