Pagophagia in the Albino Rat

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Science  25 Sep 1970:
Vol. 169, Issue 3952, pp. 1334-1336
DOI: 10.1126/science.169.3952.1334


Pagophagia, or ice-eating, is a common symptom of iron-deficiency anemia in humans. Rats made anemic by withdrawal of blood consume a significantly greater proportion of their daily water in the form of ice than nonanemic controls. Recovery from the anemia eliminates the pagophagia.

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