DDT Metabolites and Analogs: Ring Fission by Hydrogenomonas

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Science  02 Oct 1970:
Vol. 170, Issue 3953, pp. 91-92
DOI: 10.1126/science.170.3953.91


A Hydrogenomonas cleaved one of the rings of p,p'-dichlorodiphenylmethane, a product of DDT metabolism, to yield p-chlorophenylacetate and further metabolized the latter compound. Products of microbial degradation of other diphenylmethanes were also identified. Substituents on the methylene-carbon and para-chloro substitution are critical factors governing resistance of DDT and related compounds to aerobic metabolism and decomposition by the bacterium.

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