Reports

Harderian Gland: Influence on Pineal Hydroxyindole-O-Methyltransferase Activity in Neonatal Rats

See allHide authors and affiliations

Science  09 Oct 1970:
Vol. 170, Issue 3954, pp. 194-196
DOI: 10.1126/science.170.3954.194

Abstract

A circadian rhythm has been found in hydroxyindole-O-methyltransferase activity of the pineal gland of blinded 12-day-old rats. Five additional hours of lighting can partly prevent the nocturnal increase in pineal hydroxyindole-O-methyltransferase activity in such rats. Removal of the Harderian gland abolishes this response to light in 12-day-old blinded animals, giving further support to the suggestion that this gland may function as an extraretinal photosensitive organ influencing the pineal gland in blinded suckling rats.

Stay Connected to Science