Trisomy-3,4 and Triploidy (3A-ZZZW) in Chick Embryos: Autosomal and Sex Chromosomal Nondisjunction in Meiosis

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Science  23 Oct 1970:
Vol. 170, Issue 3956, pp. 457-458
DOI: 10.1126/science.170.3956.457


The first known cases of trisomy-3, trisomy-4, and triploidy (3A-ZZZW) in chickens are reported. The trisomic embryos were near death at 4 days of incubation; the triploid embryo appeared normal and probably could have developed further. Although the triploid (3A-ZZZW) was found after sampling more than 2000 embryos, the trisomic-3 and trisomic-4 embryos were discovered in the first sampling of a line of chickens selected for low egg production. These studies suggest that the sex chromosomes (Z and W), as well as the autosomes, can undergo nondisjunction in meiosis of chickens.