Phosphorylation Coupled to the Transfer of Electrons from Glutathione to Cytochrome c

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Science  30 Oct 1970:
Vol. 170, Issue 3957, pp. 552-553
DOI: 10.1126/science.170.3957.552


Formation of adenosine diphosphate from adenosine monophosphate and inorganic phosphate can be coupled to the oxidation of reduced glutathione by cytochrome c in a reaction which requires oxidized glutathione as a catalyst. The reaction occurs with purified materials in tris(hydroxymethyl)aminomethane buffer and may represent the type reaction for one or more oxidative phosphorylations.

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