Tuberculin-Active Carbohydrate That Induces Inhibition of Macrophage Migration but not Lymphocyte Transformation

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Science  06 Nov 1970:
Vol. 170, Issue 3958, pp. 637-639
DOI: 10.1126/science.170.3958.637


A tuberculin carbohydrate fraction, GAE, in sensitized animals induced a delayed type of skin reactivity and inhibited the migration of macrophages but failed to stimulate lymphocyte transformation in vitro. Tuberculin protein-containing fractions were active in each test. These results show that in vitro lymphocyte transformation is not necessarily a corollary of delayed type hypersensitivity.

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