Ribonuclease-Inhibitor System Abnormality in Dystrophic Mouse Skeletal Muscle

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Science  13 Nov 1970:
Vol. 170, Issue 3959, pp. 747-749
DOI: 10.1126/science.170.3959.747


Skeletal muscle extracts from mice with muscular dystrophy contain severalfold higher than normal levels of free alkaline ribonuclease II activity and none of the free ribonuclease inhibitor normally present. This abnormal pattern is not seen in heart or liver extracts from dystrophic mice.

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