Mixed Leukocyte Stimulation of Normal Peripheral Leukocytes by Autologous Lymphoblastoid Cells

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Science  27 Nov 1970:
Vol. 170, Issue 3961, pp. 989-990
DOI: 10.1126/science.170.3961.989


Lymphocyte culture lines can be established by using buffy coat cells from normal or diseased individuals. Established lymphocytoblasts from a normal donor were used in the one-way mixed leukocyte culture test and were found to stimulate the peripheral lymphocytes of that donor. These lymphocytoblasts were also capable of stimulating allogeneic lymphocyte populations.

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