Acute Lymphocytic Leukemia in Owl Monkeys Inoculated with Herpesvirus saimiri

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Science  19 Mar 1971:
Vol. 171, Issue 3976, pp. 1161-1163
DOI: 10.1126/science.171.3976.1161


Our study demonstrates for the first time that Herpesvirus saimiri can induce acute lymphocytic leukemia in owl monkeys (Aotus trivirgatus) and that malignant lymphoma can be induced in this species of nonhuman primates by the inoculation of the virus by various routes (intravenous, sub-cutaneous, and intradermal).

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