Kinetic Path of Genes Undergoing Selection

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Science  01 Oct 1971:
Vol. 174, Issue 4004, pp. 68-70
DOI: 10.1126/science.174.4004.68


As natural populations approach genetic equilibrium, the various genes in the population are capable of assuming intermediate distributions that might not be anticipated from either the rate of the process or the final distribution of the genes. Since it is possible that many populations have not reached genetic equilibrium, the distribution of genes in natural populations may be a reflection of the kinetic path by which the genes approach equilibrium. Attention to kinetic path provides an explanation for an apparent discrepancy in recent studies of selection in man.