Barbiturates: Radioimmunoassay

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Science  03 Dec 1971:
Vol. 174, Issue 4013, pp. 1036-1038
DOI: 10.1126/science.174.4013.1036


The development of a radioimmunoassay for barbiturate is described. The barbiturate is made antigenic by coupling it to a protein, bovine gamma globulin. The radioimmunoassay can measure as little as 5 nanograms of barbiturate.