Reports

Cooperative Critical Thermal Transition of potassium Accumulation in Smooth Muscle

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Science  09 Jun 1972:
Vol. 176, Issue 4039, pp. 1137-1139
DOI: 10.1126/science.176.4039.1137

Abstract

The steady-state levels of potassium and sodium of taenia coli of guinea are critically affected by varying temperature in the narrow range 12° to °C. For the accumulation of both cations the critical temperature, Tc, is 13.8°C the presence of millimolar external potassium. The value of Tc, decreases 10.0°C when the external potassium is raised to 10 millimolar. Since, at a fixed Temperature, the potassium accumulation follows a cooperative mechanism, the results are compared with the quantitative predictions of this approach. The itical thermal transition behavior can be described in terms of the cooperative cumulation process.

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