Crustacean Color-Change Hormone: Amino Acid Sequence and Chemical Synthesis

See allHide authors and affiliations

Science  14 Jul 1972:
Vol. 177, Issue 4044, pp. 173-175
DOI: 10.1126/science.177.4044.173


The blanching hormone of the prawn, Pandalus borealis, is pGlu-Leu-Asn-Phe-Ser-Pro-Gly-Trp-NH2. Its structure was settled by a combination of mass spectrometry and Edman-dansyl analysis of a thermolysin fragment. Confirmation of the structure was obtained by chemical synthesis from amino acids. This neurosecreted hormone is active in picogram amounts when tested in shrimps.

Stay Connected to Science