Fertility Impairment in Mice on a Low Fluoride Intake

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Science  08 Sep 1972:
Vol. 177, Issue 4052, pp. 893-894
DOI: 10.1126/science.177.4052.893


Female mice maintained on a low fluoride diet over two generations showed a progressive decline in litter production. Mice receiving the same diet supplemented with fluoride reproduced normally and at consistent intervals. Addition of fluoride to the intake of females with demonstrated impaired fertility restored their reproductive capacity.

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