Molecular Structure of LSD

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Science  10 Nov 1972:
Vol. 178, Issue 4061, pp. 614-615
DOI: 10.1126/science.178.4061.614


The molecular configuration of lysergic acid diethylamide (LSD) in crystals of the iodobenzoate has been determined by using x-ray diffraction techniques. The configuration shows strain and steric hindrance and the conformation is fixed. Some of the implications of this for the hallucinogenic activity of LSD are discussed.