Neurotrophic Effect on Isolated Chick Embryo Muscle in Culture

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Science  22 Dec 1972:
Vol. 178, Issue 4067, pp. 1298-1300
DOI: 10.1126/science.178.4067.1298


Acetylcholinesterase activity in cultures of dissociated skeletal muscle prepared from the thigh muscle of the 10-day-old chick embryo was increased by the presence of innervating spinal cord explants, spinal cord explants in a parabiotic environment, and by media containing brain-spinal cord extract.