Insulin Release by Emiocytosis: Demonstration with Freeze-Etching Technique

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Science  05 Jan 1973:
Vol. 179, Issue 4068, pp. 82-84
DOI: 10.1126/science.179.4068.82


The technique of freeze-etching for electron microscopy applied to isolated islets of Langerhans has permitted a successful evaluation of emiocytotic events on the cell surface. The frequency of these events in stimulated cells suggests that emiocytosis represents a significant mechanism for insulin release.