Chromosome Assignments in Man of the Genes for Two Hexosephosphate Isomerases

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Science  16 Mar 1973:
Vol. 179, Issue 4078, pp. 1129-1131
DOI: 10.1126/science.179.4078.1129


Thirty-seven clones of somatic cell hybrids between human and mouse cells were examined for retention of human chromosomes and expression of human constitutive enzymes. Human glucosephosphate isomerase and chromosome F-19 were retained or lost concordantly, as were human mannosephosphate isomerase and chromosome C-7. The genes for the enzymes are thus assigned to these two chromosomes.