Electrogenic Sodium Pump and High Specific Resistance in Nerve Cell Bodies of the Squid

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Science  30 Mar 1973:
Vol. 179, Issue 4080, pp. 1336-1338
DOI: 10.1126/science.179.4080.1336


An electrogenic sodium pump contributes to the membrane potential in squid nerve cell bodies, imparting a temperature dependence to the resting potential that is abolished by strophanthidin. The existence of a potential produced by the pump in the soma but not the axon is correlated with a higher membrane resistance in the soma. Thus, membranes from different parts of a neuron may have functionally significant differences in resistance.

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