Serotonin Producing Neuroepithelial Bodies in Rabbit Respiratory Mucosa

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Science  27 Apr 1973:
Vol. 180, Issue 4084, pp. 410-413
DOI: 10.1126/science.180.4084.410


The intrapulmonary lining epithelium of rabbits contains newly identified corpuscles composed of argyrophil, argentaffin, yellow fluorescent, ultrastructurally granulated and innervated epithelial cellular organs. These are proved, by electron microscopic cytochemistry and microspectrography, to be a source for intrapulmonary production of serotonin. Probably they are intrapulmonary neuroreceptor organs modulated by the central nervous system which exhibit local secretory activities.