Heart Muscle Viability following Hypoxia: Protective Effect of Acidosis

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Science  22 Jun 1973:
Vol. 180, Issue 4092, pp. 1297-1298
DOI: 10.1126/science.180.4092.1297


The mechanical performance of hypoxic heart muscle is further depressed by an acid pH. In contrast to preparations at normal or alkaline pH. however, hypoxic preparations at acid pH do not develop contracture and exhibit full recovery of mechanical activity upon reoxygenation.