Microtubule Function in Immune and Nonimmune Lymphocyte-Mediated Cytotoxicity

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Science  13 Jul 1973:
Vol. 181, Issue 4095, pp. 171-173
DOI: 10.1126/science.181.4095.171


Disaggregation of microtubular subunits in effector lymphocytes inhibits their ability to injure target cells. The inhibition is not reversed by denterium oxide, an agent known to stablize microtubular subunits.