Retinyl Acetate: Effect on Cellular Content of RNA in Epidermis in Cell Culture in Chemically Defined Medium

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Science  16 Nov 1973:
Vol. 182, Issue 4113, pp. 722-723
DOI: 10.1126/science.182.4113.722


Cell cultures of epidermis from newborn mice were established in chemically defined medium. Additions of retinyl acetate to these cultures caused a significant increase in cellular RNA content. Addition of insulin and hydrocortisone to the cultures potentiated the effect of retinyl acetate on cellular RNA content.