Thymus Adenylate Cyclase Activity during Murine Leukemogenesis

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Science  18 Jan 1974:
Vol. 183, Issue 4121, pp. 218-219
DOI: 10.1126/science.183.4121.218


Activity of thymus adenylate cyclase was more than three times higher in leukemic AKR mice than in nonleukemic AKR mice and CBA mice. Preleukemic AKR mice that had no evidence of leukemia but were expected to soon develop the disease exhibited similarly elevated activities of thymus adenylate cyclase.