Lectin Binding Saccharides on a Parasitic Protozoan

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Science  26 Apr 1974:
Vol. 184, Issue 4135, pp. 471-473
DOI: 10.1126/science.184.4135.471


Leishmania donovani promastigotes were specifically agglutinated by concanavalin A and phytohemagglutinin P. Somatic-somatic, flagellar-somatic, and flagellar-flagellar type agglutination was observed with the lectins. Enzyme-treated promastigotes gave reduced lectin agglutination reactions. The results suggest that complex saccharide moieties are randomly distributed on the surface of this organism.