Microbodies (Peroxisomes) Containing Catalase in Myocardium: Morphological and Biochemical Evidence

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Science  19 Jul 1974:
Vol. 185, Issue 4147, pp. 271-273
DOI: 10.1126/science.185.4147.271


Microbodies characterized by a single limiting membrane and finely granular matrix occur in mouse myocardium and appear in close spatial relation to mitochondria and sarcoplasmic reticulum. The presence of catalase in the microbodies is revealed cytochemically and confirmed biochemically by direct measurement of its activity in myocardial tissue fractions. It is suggested that the microbodies may play an important role in myocardial lipid metabolism.