Vascular and brain dopamine beta-hydroxylase activity in young spontaneously hypertensive rats

See allHide authors and affiliations

Science  23 Jan 1976:
Vol. 191, Issue 4224, pp. 290-291
DOI: 10.1126/science.1858


Dopamine beta-hydroxylase activity was higher in mesenteric vessels, adrenal glands, and serum of 3-week-old spontaneously hypertensive rats but lower in the locus coeruleus than it was in the control Wistar-Kyoto rats. The results support the concept that the nervous system is an important regulator of blood pressure.

Stay Connected to Science