Stress-induced hyperphagia and obesity in rats: a possible model for understanding human obesity

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Science  23 Jan 1976:
Vol. 191, Issue 4224, pp. 310-312
DOI: 10.1126/science.1246617


Mild tail pinch administered to rats several times daily in the presence of sweetened mild induced immediate hyperphagia and led to considerable gain in body weight. Parallels are drawn with stress-induced hyperhagia and altered affective states in obese humans.

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