beta-D-galactosidase activity in single yeast cells during cell cycle of Saccharomyces lactis

See allHide authors and affiliations

Science  26 Mar 1976:
Vol. 191, Issue 4233, pp. 1283-1284
DOI: 10.1126/science.1257751


Single Saccharomyces lactis cells taken from a random population were assayed for beta-D-galactosidase activity under a microscope equipped for fluorogenic measurements. The cells were also photographed, and enzymatic activity was correlated to the size of cell buds. A perodic pattern of enzyme synthesis was found during the cell cycle.